METABOLIC REPROGRAMMING AND CROSSTALK OF CANCER-RELATED FIBROBLASTS AND IMMUNE CELLS IN THE TUMOR MICROENVIRONMENT

Metabolic reprogramming and crosstalk of cancer-related fibroblasts and immune cells in the tumor microenvironment

It is notorious that cancer cells alter their metabolism to adjust to harsh environments of hypoxia and nutritional starvation.Metabolic reprogramming most often occurs in the tumor microenvironment (TME).TME is defined Mobility as the cellular environment in which the tumor resides.This includes surrounding blood vessels, fibroblasts, immune cells

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